Cinnamon, an effective anti-obesity agent: Evidence from an umbrella meta-analysis

Majid Keramati; Vali Musazadeh; Mahsa Malekahmadi; Parmida Jamilian; Parsa Jamilian; Zohre Ghoreishi; Meysam Zarezadeh; Alireza Ostadrahimi

doi:10.1111/jfbc.14166

Cinnamon, an effective anti-obesity agent: Evidence from an umbrella meta-analysis

J Food Biochem. 2022 Aug;46(8):e14166. doi: 10.1111/jfbc.14166. Epub 2022 Apr 1.

Authors

Majid Keramati^{1

2}, Vali Musazadeh^{1

2}, Mahsa Malekahmadi^{3

4}, Parmida Jamilian⁵, Parsa Jamilian⁶, Zohre Ghoreishi⁷, Meysam Zarezadeh^{1

8}, Alireza Ostadrahimi⁸

Affiliations

¹ Student Research Committee, Nutrition Research Center, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
² School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
³ Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
⁴ School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran.
⁵ School of Pharmacy and Bio Engineering, Keele University, Keele, UK.
⁶ Keele University School of Medicine, Keele University, Keele, UK.
⁷ Department of Clinical Nutrition, Faculty of Nutrition and Food Science, Tabriz University of Medical Sciences, Tabriz, Iran.
⁸ Nutrition Research Center, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.

PMID: 35365881
DOI: 10.1111/jfbc.14166

Abstract

The evidence provided by meta-analyses on the beneficial impacts of cinnamon supplementation on anthropometric indices are still conflicting. Present study's aim was to evaluate the effects of cinnamon on obesity indices by an umbrella meta-analysis. The electronic databases including Web of Science, PubMed, EMBASE, Scopus were systematically searched up to March 2021. Data for the effects of cinnamon on anthropometric indices were collected from the meta-analyses. An umbrella meta-analysis was carried out using a random-effects model. The pooled effects of 7 meta-analyses showed that cinnamon supplementation significantly reduced body weight (ES: -0.67 kg; 95% CI: -0.99, -0.35, p ˂ .001), body mass index (ES: -0.45 kg/m² ; 95% CI: -0.57, -0.33, p ˂ .001) in comparison to control group. However, the effects of cinnamon on waist circumference (ES: -1.05 cm; 95% CI: -2.26, 0.15, p = .087) were not considerable. According to results, cinnamon could be suggested as a complementary weight loss agent. Favorable results were obtained at a dose of ≥3 g/day. In this study, a comprehensive study was performed on meta-analyses performed on the effect of cinnamon on anthropometric indices. This study could be considered as a final conclusion about the effect of cinnamon on anthropometric indices. The results of this study showed that supplementation with cinnamon significantly reduces BMI and body weight. The impacts were greater in doses of ≥3 g/day and in PCOS patients. PRACTICAL APPLICATIONS: In this study, a comprehensive study was performed on meta-analyses performed on the effect of cinnamon on anthropometric indices. This study could be considered as a final conclusion about the effect of cinnamon on anthropometric indices. The results of this study showed that supplementation with cinnamon significantly reduces BMI and body weight. The impacts were greater in doses of ≥3 g/day and in PCOS patients.

Keywords: anthropometric indices; body mass index; cinnamon; obesity; umbrella meta-analysis.

Publication types

Meta-Analysis
Review
Systematic Review
Research Support, Non-U.S. Gov't

MeSH terms

Anti-Obesity Agents*
Body Weight
Cinnamomum zeylanicum
Dietary Supplements
Female
Humans
Polycystic Ovary Syndrome*

Substances

Anti-Obesity Agents