Molecularly imprinted sensing platform based on electrochemically modified graphite paper for efficient detection of 3-monochloropropane-1,2-diol

Abstract

In this study, a molecularly imprinted polymer (MIP) electrochemical sensor based on electrochemically modified graphite paper (EM-GP) was developed for the detection of 3-MCPD for the first time. To this end, Prussian blue (PB) was electrodeposited on EM-GP to yield uniformly distributed PtNPs. The successful preparation of Pt@PB/EM-GP was verified by SEM, Raman spectroscopy, XRD,XPS, and EDS. MIP was then prepared by CV electropolymerization with template molecules (3-MCPD), and density functional theory (DFT) at M06-2X/6-31 + g (d,p) level was used to calculate the molecular-level interaction between 3-MCPD and MIP. Under the optimum conditions, the dynamic linear range of the sensing platform varied from 1 × 10^-8mol/L to 5 × 10^-5mol/L with a detection limit estimated to 5 × 10^-9 mol/L (S/N = 3). Overall, these findings look promising for the construction of selective and quick detection platforms of 3-MCPD in food samples.

Keywords: 3-MCPD; Electrochemical sensor; Electrochemically modified graphite paper; Molecularly imprinted polymer.