Organization and epigenomic control of RNA polymerase III-transcribed genes in plants

Guillaume Hummel; Chang Liu

doi:10.1016/j.pbi.2022.102199

Organization and epigenomic control of RNA polymerase III-transcribed genes in plants

Curr Opin Plant Biol. 2022 Jun:67:102199. doi: 10.1016/j.pbi.2022.102199. Epub 2022 Mar 29.

Authors

Guillaume Hummel¹, Chang Liu²

Affiliations

¹ Institute of Biology, University of Hohenheim, Garbenstraße 30, 70599, Stuttgart, Germany. Electronic address: guillaume.hummel@uni-hohenheim.de.
² Institute of Biology, University of Hohenheim, Garbenstraße 30, 70599, Stuttgart, Germany. Electronic address: chang.liu@uni-hohenheim.de.

PMID: 35364484
DOI: 10.1016/j.pbi.2022.102199

Abstract

The genetic information linearly scripted in chromosomes is wrapped in a ribonucleoprotein complex called chromatin. The adaptation of its compaction level and spatiotemporal organization refines gene expression in response to developmental and environmental cues. RNA polymerase III (RNAPIII) is responsible for the biogenesis of elementary non-coding RNAs. Their genes are subjected to high duplication and mutational rates, and invade nuclear genomes. Their insertion into different epigenomic environments raises the question of how chromatin packing affects their individual transcription. In this review, we provide a unique perspective to this issue in plants. In addition, we discuss how the genomic organization of RNAPIII-transcribed loci, combined with epigenetic differences, might participate to plant trait variations.

Keywords: 3D genome; Chromatin; Epigenome; Non-coding RNAs; Plant; Polymerase competitions; RNA polymerase III; Trait variation; Transcription.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Chromatin / genetics
Epigenesis, Genetic
Epigenomics*
Plants / genetics
Plants / metabolism
RNA Polymerase III* / genetics
RNA Polymerase III* / metabolism
Transcription, Genetic

Substances

Chromatin
RNA Polymerase III