Characterizing the landscape of evolvability

Faruck Morcos

doi:10.1038/s41559-022-01731-0

Characterizing the landscape of evolvability

Nat Ecol Evol. 2022 May;6(5):500-501. doi: 10.1038/s41559-022-01731-0.

Author

Faruck Morcos^{1

2

3}

Affiliations

¹ Department of Biological Sciences, University of Texas at Dallas, Richardson, TX, USA. faruckm@utdallas.edu.
² Center for Systems Biology, University of Texas at Dallas, Richardson, TX, USA. faruckm@utdallas.edu.
³ Department of Bioengineering, University of Texas at Dallas, Richardson, TX, USA. faruckm@utdallas.edu.

Abstract

A framework to experimentally traverse the large space of functionally neutral variants in a toxin–antitoxin protein complex reveals insights on evolvability and entrenchment of molecular interactions.

Publication types

Comment

MeSH terms

Models, Genetic*
Selection, Genetic*

Grants and funding

R35 GM133631/GM/NIGMS NIH HHS/United States