1 Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha, NE, USA. Electronic address: izucker@unmc.edu.
2 King's British Heart Foundation Centre of Research Excellence, School of Cardiovascular and Metabolic Medicine & Sciences, Kings College London 150 Stamford Street, London, SE1 9NH, UK. Electronic address: giovanni.mann@kcl.ac.uk.
3 Department of Clinical Experimental Medicine, Brighton and Sussex Medical School, Brighton, UK. Electronic address: p.ghezzi@bsms.ac.uk.