Diagnostic and Prognostic Implications of GNAS Inactivation in Sonic Hedgehog-Activated Medulloblastoma: Case Report with Comprehensive Molecular Profiling and Review of Literature

JCO Precis Oncol. 2022 Mar:6:e2100403. doi: 10.1200/PO.21.00403.
No abstract available

Publication types

  • Case Reports
  • Review

MeSH terms

  • Cerebellar Neoplasms* / diagnosis
  • Chromogranins / genetics
  • GTP-Binding Protein alpha Subunits, Gs / genetics
  • Hedgehog Proteins / genetics
  • Humans
  • Medulloblastoma* / diagnosis
  • Prognosis
  • Signal Transduction

Substances

  • Chromogranins
  • Hedgehog Proteins
  • GNAS protein, human
  • GTP-Binding Protein alpha Subunits, Gs