Ampullary cancer detected upon re-examination in a patient initially diagnosed as cancer of unknown primary

Yasuharu Kawamoto; Kenji Ikezawa; Shinichiro Hasegawa; Hiroshi Wada; Toshihiro Kudo; Shigenori Nagata; Kazuyoshi Ohkawa

doi:10.1002/jgh3.12710

Ampullary cancer detected upon re-examination in a patient initially diagnosed as cancer of unknown primary

JGH Open. 2022 Feb 8;6(3):222-224. doi: 10.1002/jgh3.12710. eCollection 2022 Mar.

Authors

Yasuharu Kawamoto¹, Kenji Ikezawa¹, Shinichiro Hasegawa², Hiroshi Wada², Toshihiro Kudo³, Shigenori Nagata⁴, Kazuyoshi Ohkawa¹

Affiliations

¹ Department of Hepatobiliary and Pancreatic Oncology Osaka International Cancer Institute Osaka Japan.
² Department of Gastroenterological Surgery Osaka International Cancer Institute Osaka Japan.
³ Department of Medical Oncology Osaka International Cancer Institute Osaka Japan.
⁴ Department of Diagnostic Pathology and Cytology Osaka International Cancer Institute Osaka Japan.

Abstract

In patients with cancer of unknown primary (CUP), the efficiency of reexamination in the improvement of the prognosis has not been demonstrated yet. In the present case, ampullary adenocarcinoma, initially diagnosed as CUP, was revealed by endoscopic forceps biopsy for the ampullary lesion progressing over time. Reexamination of the primary site in patients with CUP could contribute to better treatment options and improvement in the prognosis.

Keywords: cancer of unknown primary site; conversion surgery; duodenal papillary carcinoma; endoscopic ultrasound.