Eye-Tracking Studies in Adults with Autism Spectrum Disorder: A Systematic Review and Meta-analysis

J Autism Dev Disord. 2023 Jun;53(6):2430-2443. doi: 10.1007/s10803-022-05524-z. Epub 2022 Mar 30.

Abstract

Eye-tracking studies have shown potential in effectively discriminating between autism spectrum disorder (ASD) and non-ASD groups. The main objective of the present study was to conduct a systematic review and meta-analysis of eye-tracking studies in adults with ASD. A total of 22 studies were included for meta-analysis. Eyes and Non-Social regions proved better for discriminating between ASD and non-ASD adults, while fixation duration seems to be the outcome to choose. Active engaged tasks seem to reduce differences between ASD and non-ASD adults, regardless of the emotional content of the stimuli/task. Proportional fixation duration on eyes and non-social areas in non-active tasks (e.g. free viewing) seems to be the best eye-tracking design for increasing the sensitivity and specificity in ASD adults.

Keywords: Adults; Autism spectrum disorder; Eye-tracking; Meta-analysis; Systematic review.

Publication types

  • Meta-Analysis
  • Systematic Review

MeSH terms

  • Adult
  • Autism Spectrum Disorder* / diagnosis
  • Autism Spectrum Disorder* / psychology
  • Emotions
  • Eye-Tracking Technology
  • Humans
  • Photic Stimulation
  • Sensitivity and Specificity