68 Ga-FAPI-04 Versus 18 F-FDG PET/CT in a Case With Intimal Sarcoma of the Pulmonary Artery

Clin Nucl Med. 2022 Aug 1;47(8):748-750. doi: 10.1097/RLU.0000000000004141. Epub 2022 Mar 30.

Abstract

Intimal sarcoma of the pulmonary artery is a rare entity, mimicking acute or chronic pulmonary thromboembolism. We describe 68 Ga-FAPI-04 and 18 F-FDG PET/CT findings in a case with intimal sarcoma of the pulmonary artery. The intrapulmonary artery tumor showed inhomogeneously increased FDG and FAPI uptake. Compared with FDG PET/CT, FAPI PET/CT more clearly delineated the tumor partially because of a very low background FAPI activity in the walls of the main pulmonary artery and right ventricle, which showed diffuse FDG uptake.

MeSH terms

  • Fluorodeoxyglucose F18
  • Humans
  • Positron Emission Tomography Computed Tomography
  • Pulmonary Artery / diagnostic imaging
  • Pulmonary Artery / pathology
  • Quinolines
  • Sarcoma* / diagnostic imaging
  • Sarcoma* / pathology
  • Soft Tissue Neoplasms*

Substances

  • 68Ga-FAPI
  • Quinolines
  • Fluorodeoxyglucose F18