Dual-responsive polypeptide nanoparticles attenuate tumor-associated stromal desmoplasia and anticancer through programmable dissociation

Affiliations

• ¹ Department of Materials Science and Engineering, National Tsing Hua University, Taiwan; Department of Bioengineering, University of Illinois at Urbana-Champaign, United States.
• ² Department of Materials Science and Engineering, National Tsing Hua University, Taiwan.
• ³ Division of Neurosurgery, Department of Surgery, National Taiwan University Hospital, Taiwan; College of Biological Science and Technology, National Chiao Tung University, Taiwan.
• ⁴ Division of Plastic Surgery, Department of Surgery, National Taiwan University Hospital, Taiwan; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taiwan; Research Center for Developmental Biology and Regenerative Medicine, National Taiwan University, Taiwan.
• ⁵ Institute of Biomedical Engineering, National Tsing Hua University, Taiwan.
• ⁶ Department of Materials Science and Engineering, National Tsing Hua University, Taiwan. Electronic address: twwang@mx.nthu.edu.tw.