Tackling variants with antibodies

Elizabeth H Aitken; Stephen J Rogerson

doi:10.7554/eLife.77751

Tackling variants with antibodies

Elife. 2022 Mar 28:11:e77751. doi: 10.7554/eLife.77751.

Authors

Elizabeth H Aitken¹, Stephen J Rogerson¹

Affiliation

¹ Department of Infectious Diseases, Department of Microbiology and Immunology, at the Doherty Institute, University of Melbourne, Melbourne, Australia.

Abstract

Antibodies targeting the protein that causes placental malaria can recognise multiple variants of the protein, which may help guide the development of new vaccines to protect pregnant women from malaria.

Keywords: P. falciparum; Placental malaria; VAR2CSA; blocking antibody; immunology; infectious disease; inflammation; malaria; microbiology; pregnancy; vaccine; variant.

Publication types

Editorial
Comment

MeSH terms

Antibodies, Protozoan
Female
Humans
Malaria* / prevention & control
Malaria, Falciparum*
Placenta
Pregnancy
Pregnancy Complications, Parasitic*

Substances

Antibodies, Protozoan