[Diagnosis and Treatment of Eosinophilic Esophagitis]

Korean J Gastroenterol. 2022 Mar 25;79(3):99-108. doi: 10.4166/kjg.2021.119.
[Article in Korean]

Abstract

Eosinophilic esophagitis (EoE) is a chronic, immune/antigen-mediated esophageal disease characterized by symptoms of esophageal dysfunction and eosinophil-predominant inflammation. The diagnostic criteria for EoE have changed with our growing knowledge over the past two decades. Esophageal eosinophilia, which responds histologically to a proton pump inhibitor (PPI) is not a distinct disease but a subset of EoE. An endoscopic scoring system that relies on the assessment of exudates, rings, edema, furrows, and strictures is a useful tool for assessing endoscopic severity. PPIs are regarded as safe and effective first-line treatments for EoE. Oral topical corticosteroids or dietary therapy are also options for first-line treatment. Endoscopic dilation is effective for relieving the dysphagia symptoms of a patient with an esophageal stricture.

Keywords: Eosinophilic esophagitis; Proton pump inhibitors; Steroids.

Publication types

  • Review

MeSH terms

  • Dilatation
  • Enteritis
  • Eosinophilia
  • Eosinophilic Esophagitis* / diagnosis
  • Eosinophilic Esophagitis* / drug therapy
  • Gastritis
  • Humans
  • Proton Pump Inhibitors / therapeutic use

Substances

  • Proton Pump Inhibitors

Supplementary concepts

  • Eosinophilic enteropathy