Effects of cigarette abstinence on negative and positive affect by depression symptom levels: A lab study

J Affect Disord. 2022 Jun 15:307:163-170. doi: 10.1016/j.jad.2022.03.052. Epub 2022 Mar 24.

Abstract

Background: High negative affect and low positive affect are key depression-related states that may be greater following acute tobacco abstinence. This study aimed to test associations between depression symptom levels and acute tobacco abstinence with negative affect and positive affect.

Methods: Following a baseline session, participants attended two counterbalanced laboratory sessions (non-abstinent, abstinent) and completed measures of positive and negative affect at rest (i.e., when not completing a task) and during a film clip task.

Results: Individuals with elevated depression symptoms had higher negative affect and lower positive affect at rest and during the film clip task compared to individuals with low depression symptoms. There was no interaction of depression symptom levels and abstinence on negative and positive affect at rest. There was an interaction of depression symptom level and abstinence on negative and positive affect during the film clip task. Individuals with elevated depression showed significant differences in positive and negative affect between the abstinent and non-abstinent session, but no significant abstinence effects were noted in individuals with low depression symptoms.

Limitations: The study included a non-treatment seeking sample and experimentally induced acute cigarette abstinence. We excluded for the use of smoking cessation medications that are also used to treat depression, classified depression levels using dichotomized CES-D scores, and used self-report measures of affect.

Conclusions: Results of this study suggest individuals with elevated depression symptoms who smoke experience elevated negative affect and lower positive affect and cigarette abstinence may uniquely alter affective reactivity in individuals with elevated depression symptoms.

Keywords: Cigarette smoking; Depression symptoms; Film clip task; Laboratory study; Negative affect; Positive affect.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Depression
  • Humans
  • Self Report
  • Smoking Cessation* / psychology
  • Substance Withdrawal Syndrome* / psychology
  • Tobacco Products*
  • Tobacco Use Disorder* / psychology