Is intravenous magnesium sulphate safe to be administered outside the critical care setting?

Amanda de Havilland; Gopakumar Hariharan; Ramaa Puvvadi

doi:10.1111/jpc.15951

Is intravenous magnesium sulphate safe to be administered outside the critical care setting?

J Paediatr Child Health. 2022 May;58(5):924-928. doi: 10.1111/jpc.15951. Epub 2022 Mar 26.

Authors

Amanda de Havilland¹, Gopakumar Hariharan², Ramaa Puvvadi³

Affiliations

¹ JCU College of Medicine and Dentistry, Mackay Base Hospital, Mackay, Queensland, United States.
² Department of Child and Adolescent Health Unit, James Cook University, Mackay Base Hospital, Mackay, Queensland, United States.
³ Department of Paediatrics, Townsville University Hospital, Townsville, Queensland, United States.

PMID: 35338747
DOI: 10.1111/jpc.15951

Abstract

Aim: To review current evidence regarding the safety of intravenous bolus magnesium sulphate for the treatment of children with acute severe asthma in the non-critical care setting.

Methods: MEDLINE via Ovid, Embase and the Cochrane Library were searched for relevant articles.

Results: Four hundred and eighteen articles were identified during the initial search after removal of duplicates. Eighty full-text articles were selected for review and 16 included as relevant to the clinical question.

Conclusions: Current evidence suggests that bolus intravenous magnesium sulphate is safe to be administered in non-critical care settings provided that line of sight nursing and cardiorespiratory monitoring are available.

Keywords: asthma; magnesium; paediatrics; sulphate.

Publication types

Review

MeSH terms

Child
Critical Care*
Humans
Injections, Intravenous
Magnesium Sulfate* / adverse effects

Substances

Magnesium Sulfate