Preparation and Synthetic Applications of Five-to-Seven-Membered Cyclic α-Diazo Monocarbonyl Compounds

Daniil Zhukovsky; Dmitry Dar'in; Olga Bakulina; Mikhail Krasavin

doi:10.3390/molecules27062030

Preparation and Synthetic Applications of Five-to-Seven-Membered Cyclic α-Diazo Monocarbonyl Compounds

Molecules. 2022 Mar 21;27(6):2030. doi: 10.3390/molecules27062030.

Authors

Daniil Zhukovsky¹, Dmitry Dar'in², Olga Bakulina², Mikhail Krasavin^{2

3}

Affiliations

¹ Research & Development Department, BratskChemSyntez LLC, PharmaSyntez Company, 5A/1 Kommunalnaya St., 665717 Bratsk, Russia.
² Institute of Chemistry, Saint Petersburg State University, 199034 Saint Petersburg, Russia.
³ Immanuel Kant Baltic Federal University, 236041 Kaliningrad, Russia.

Abstract

The reactivity of cyclic α-diazo monocarbonyl compounds differs from that of their acyclic counterparts. In this review, we summarize the current literature available on the synthesis and synthetic applications of three major classes of cyclic α-diazo monocarbonyl compounds: α-diazo ketones, α-diazo lactones and α-diazo lactams.

Keywords: preparation; synthetic applications; α-diazo ketones; α-diazo lactams; α-diazo lactones.

Publication types

Review

MeSH terms

Azo Compounds*
Ketones*
Lactams
Lactones

Substances

Azo Compounds
Ketones
Lactams
Lactones

Grants and funding

19-75-30008/Russian Science Foundation