Sleep and gynecological cancer outcomes: opportunities to improve quality of life and survival

Int J Gynecol Cancer. 2022 May 3;32(5):669-675. doi: 10.1136/ijgc-2022-003404.

Abstract

Sleep is important for immune function, metabolic function and physical repair. Sleep is more commonly disrupted in women compared with men and is disrupted by surgery, chemotherapy, and cancer itself, making gynecological oncology patients at higher risk of insomnia and sleep disruption. Insomnia and sleep disruption are linked to increased pain, poorer quality of life, depression, and anxiety which can all negatively affect patient outcomes. A number of environmental, behavioral, and pharmacological interventions have been investigated to improve patient sleep and aid in the recovery process. It is vital to understand and address patient sleep quality in order to give patients the highest quality care and improve outcomes.

Keywords: Gynecologic Surgical Procedures; Ovarian Cancer; Postoperative Period; Surgical Oncology; Uterine Cancer.

Publication types

  • Review
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Depression
  • Female
  • Genital Neoplasms, Female* / therapy
  • Humans
  • Male
  • Quality of Life
  • Sleep
  • Sleep Initiation and Maintenance Disorders*