Systemic Therapy and Its Surgical Implications in Patients with Resectable Liver Colorectal Cancer Metastases. A Report from the Western Canadian Gastrointestinal Cancer Consensus Conference

Shahid Ahmed; Nicholas Bosma; Michael Moser; Shahida Ahmed; Bryan Brunet; Janine Davies; Corinne Doll; Dorie-Anna Dueck; Christina A Kim; Shuying Ji; Duc Le; Richard Lee-Ying; Howard Lim; John Paul McGhie; Karen Mulder; Jason Park; Deepti Ravi; Daniel J Renouf; Devin Schellenberg; Ralph P W Wong; Adnan Zaidi

doi:10.3390/curroncol29030147

Systemic Therapy and Its Surgical Implications in Patients with Resectable Liver Colorectal Cancer Metastases. A Report from the Western Canadian Gastrointestinal Cancer Consensus Conference

Curr Oncol. 2022 Mar 8;29(3):1796-1807. doi: 10.3390/curroncol29030147.

Authors

Shahid Ahmed¹, Nicholas Bosma², Michael Moser³, Shahida Ahmed⁴, Bryan Brunet^{1

5}, Janine Davies², Corinne Doll⁶, Dorie-Anna Dueck^{1

7}, Christina A Kim⁴, Shuying Ji⁸, Duc Le^{1

5}, Richard Lee-Ying⁶, Howard Lim², John Paul McGhie⁹, Karen Mulder¹⁰, Jason Park¹¹, Deepti Ravi¹², Daniel J Renouf², Devin Schellenberg¹³, Ralph P W Wong⁴, Adnan Zaidi^{1

7}

Affiliations

¹ Saskatoon Cancer Center, Saskatchewan Cancer Agency, 20 Campus Drive, University of Saskatchewan, Saskatoon, SK S7N 4H4, Canada.
² British Columbia Cancer Agency, Vancouver, BC V5Z 4E6, Canada.
³ Department of Surgery, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.
⁴ CancerCare Manitoba, Winnipeg, MB R3E 0V9, Canada.
⁵ Department of Radiation Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.
⁶ Arnie Charbonneau Cancer Institute, Alberta Health Service, Calgary, AB T2N 4Z6, Canada.
⁷ Department of Medical Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.
⁸ Shared Health, Winnipeg, MB R3B 2K6, Canada.
⁹ British Columbia Cancer Agency, Victoria, BC V8R 6V5, Canada.
¹⁰ Cross Cancer Institute, Alberta Health Services, Edmonton, AB T6G 1Z2, Canada.
¹¹ Department of Surgery, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.
¹² Saskatchewan Health Authority, Saskatoon, SK S7K 0M7, Canada.
¹³ British Columbia Cancer Agency, Surrey, BC V3V 1Z2, Canada.

Abstract

The Western Canadian Gastrointestinal Cancer Consensus Conference (WCGCCC) convened virtually on 4 November 2021. The WCGCCC is an interactive multi-disciplinary conference attended by health care professionals, including surgical, medical, and radiation oncologists; pathologists; radiologists; and allied health care professionals from across four Western Canadian provinces, British Columbia, Alberta, Saskatchewan, and Manitoba, who are involved in the care of patients with gastrointestinal cancer. They participated in presentation and discussion sessions for the purpose of developing recommendations on the role of systemic therapy and its optimal sequence in patients with resectable metastatic colorectal cancer.

Keywords: CRLM; adjuvant therapy; chemotherapy; colorectal liver metastases; consensus; metastasectomy; surgery; systemic therapy.

Publication types

Consensus Development Conference
Research Support, Non-U.S. Gov't

MeSH terms

Alberta
Gastrointestinal Neoplasms* / therapy
Humans
Liver Neoplasms* / secondary
Liver Neoplasms* / surgery
Rectal Neoplasms* / pathology
Rectal Neoplasms* / therapy