Noncanonical Sensing Mechanisms for Bacillus subtilis Chemoreceptors

J Bacteriol. 2022 Apr 19;204(4):e0002722. doi: 10.1128/jb.00027-22. Epub 2022 Mar 24.

Abstract

Bodhankar et al. reported a noncanonical sensing mechanism that involves signal interaction with the McpA chemoreceptor signaling domain resulting in a chemorepellence response of Bacillus subtilis. The identified repellent binding site is analogous to that for attractant binding in McpB, another B. subtilis chemoreceptor.

Keywords: Bacillus subtilis; chemoattraction; chemoreceptor; chemorepellence; chemotaxis; sensing.

Publication types

  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Bacillus subtilis* / metabolism
  • Bacterial Proteins / metabolism
  • Chemoreceptor Cells / physiology
  • Chemotaxis* / physiology
  • Membrane Proteins / genetics
  • Membrane Proteins / metabolism
  • Methyl-Accepting Chemotaxis Proteins / metabolism

Substances

  • Bacterial Proteins
  • Membrane Proteins
  • Methyl-Accepting Chemotaxis Proteins