Autonomic aging - A dataset to quantify changes of cardiovascular autonomic function during healthy aging

Sci Data. 2022 Mar 23;9(1):95. doi: 10.1038/s41597-022-01202-y.

Abstract

Autonomic regulation of blood pressure and cardiac rhythm progressively declines with increasing age. Impaired cardiovascular control promotes a variety of age-related cardio-vascular conditions. This study aims to provide a database of high-resolution biological signals to describe the effect of healthy aging on cardiovascular regulation. Electrocardiogram and continuous non-invasive blood pressure signals were recorded simultaneously at rest in 1,121 healthy volunteers. With this database, we provide raw signals as well as basic demographic information such as gender and body mass index. To demonstrate validity of the acquired data, we present the well-known decline of heart rate variability with increasing age in this database.

Publication types

  • Dataset
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aging* / physiology
  • Autonomic Nervous System* / physiology
  • Cardiovascular System*
  • Healthy Aging
  • Humans