Background: Obstructive jaundice caused by primary duodenal lymphoma is a rare disease.
Case presentation: We reported a 59-year-old man who underwent endoscopic ultrasonography for obstructive jaundice and found a duodenal papilla tumor. Light microscopy revealed a non-Hodgkin's lymphoma. Immunohistochemical staining showed that the tumor was aggressive B-cell lymphoma. We carried out molecular targeted therapy combined with CHOP regimen chemotherapy.
Conclusion: Surgery plays an important role in resolving obstructive jaundice when accurate histological diagnosis cannot be made. After diagnosis, chemotherapy should play a central role in treatment.
Keywords: Duodenal papilla; Duodenum; Jaundice; Lymphoma.
© 2022. The Author(s).