Efficacy and safety of preoperative embolization in carotid body tumor treatment: A propensity score matching retrospective cohort study

Zhaoyu Wu; Peng Qiu; Hongji Pu; Kaichuang Ye; Guang Liu; Weimin Li; Xiaobing Liu; Minyi Yin; Mier Jiang; Jinbao Qin; Xinwu Lu; Zhen Zhao

doi:10.1002/hed.27038

Efficacy and safety of preoperative embolization in carotid body tumor treatment: A propensity score matching retrospective cohort study

Head Neck. 2022 Jun;44(6):1414-1421. doi: 10.1002/hed.27038. Epub 2022 Mar 23.

Authors

Zhaoyu Wu^{1

2}, Peng Qiu^{1

2}, Hongji Pu^{1

2}, Kaichuang Ye^{1

2}, Guang Liu^{1

2}, Weimin Li^{1

2}, Xiaobing Liu^{1

2}, Minyi Yin^{1

2}, Mier Jiang^{1

2}, Jinbao Qin^{1

2}, Xinwu Lu^{1

2}, Zhen Zhao^{1

2}

Affiliations

¹ Department of Vascular Surgery, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
² Vascular Center of Shanghai Jiaotong University, Shanghai, China.

PMID: 35319144
DOI: 10.1002/hed.27038

Abstract

Background: To assess the efficacy and safety of preoperative embolization (PE) in patients with carotid body tumor (CBTs).

Methods: In a single-center retrospective cohort study, 127 patients underwent surgical resection of CBTs from January 2003 to December 2019. One-to-one propensity score matching was conducted between patients with or without PE.

Results: Thirty-two (25.2%) patients received PE. After propensity score matching, no statistically significant differences were found in the baseline characteristics of 28 patients in each group. Compared with NPE group, operative time and estimated blood loss (EBL) were significantly reduced in the PE group. The incidence of stroke, perioperative complications, intraoperative blood transfusion, vascular reconstruction, hospital stay, tumor recurrence, and all-cause mortality were not different between the PE and NPE group.

Conclusions: Preoperative embolization was efficient and safe with a reduction of intraoperative blood loss and operative time during CBT resection.

Keywords: Shamblin's classification; carotid body tumor; paragangliomas; preoperative embolization; surgical resection.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Carotid Body Tumor* / pathology
Carotid Body Tumor* / surgery
Embolization, Therapeutic*
Humans
Neoplasm Recurrence, Local
Propensity Score
Retrospective Studies
Treatment Outcome