Traditional Uses, Phytochemistry, Pharmacology and Toxicology of Rhizoma phragmitis: A Narrative Review

Chin J Integr Med. 2022 Dec;28(12):1127-1136. doi: 10.1007/s11655-022-3572-1. Epub 2022 Mar 23.

Abstract

Rhizoma phragmitis is a common Chinese herbal medicine whose effects are defined as 'clearing heat and fire, promoting fluid production to quench thirst, eliminating irritability, stopping vomiting, and disinhibiting urine'. During the Novel Coronavirus epidemic in 2020, the Weijing Decoction and Wuye Lugen Decoction, with Rhizoma phragmitis as the main herbal component, were included in The Pneumonia Treatment Protocol for Novel Coronavirus Infection (Trial Version 5) due to remarkable antiviral effects. Modern pharmacological studies have shown that Rhizoma phragmitis has antiviral, antioxidative, anti-inflammatory, analgesic, and hypoglycemic functions, lowers blood lipids and protects the liver and kidney. This review aims to provide a systematic summary of the botany, traditional applications, phytochemistry, pharmacology and toxicology of Rhizoma phragmitis.

Keywords: Chinese medicine; Rhizoma phragmitis; pharmacology; phytochemistry.

Publication types

  • Review

MeSH terms

  • Antioxidants / therapeutic use
  • Antiviral Agents / pharmacology
  • Antiviral Agents / therapeutic use
  • COVID-19 Drug Treatment*
  • Drugs, Chinese Herbal* / pharmacology
  • Drugs, Chinese Herbal* / therapeutic use
  • Ethnopharmacology
  • Humans
  • Medicine, Chinese Traditional
  • Phytochemicals / pharmacology
  • Phytochemicals / therapeutic use
  • Plant Extracts / pharmacology
  • Rhizome

Substances

  • Plant Extracts
  • Drugs, Chinese Herbal
  • Antioxidants
  • Antiviral Agents
  • Phytochemicals