Shortening of interpupillary distance after topical prostaglandin analog eye drop application in an ophthalmic surgeon: A case report

Ichiya Sano; Hidenori Takahashi; Takeshi Hara; Hidetoshi Kawashima; Chihiro Mayama

doi:10.1016/j.ajoc.2022.101480

Shortening of interpupillary distance after topical prostaglandin analog eye drop application in an ophthalmic surgeon: A case report

Am J Ophthalmol Case Rep. 2022 Mar 15:26:101480. doi: 10.1016/j.ajoc.2022.101480. eCollection 2022 Jun.

Authors

Ichiya Sano¹, Hidenori Takahashi², Takeshi Hara³, Hidetoshi Kawashima², Chihiro Mayama⁴

Affiliations

¹ Department of Ophthalmology, Shimane University, 89-1, Enya Izumo Shimane, Japan.
² Department of Ophthalmology, Jichi Medical University, 3311-1, Yakushiji Shimotsuke, Tochigi, Japan.
³ Hara Eye Hospital, 1-1-11, Nishi Utsunomiya, Tochigi, Japan.
⁴ Department of Ophthalmology, Japan Community Health Care Organization Tokyo Shinjuku Medical Center, 5-1 Tsukudo-cho, Shinjuku-ku, Tokyo, Japan.

Abstract

Purpose: This study reports a case of interpupillary distance (IPD) shortening after instillation of topical prostaglandin analog (PGA) eye drops.

Observations: The patient was a 36-year-old ophthalmic vitreoretinal surgeon from Tochigi, Japan, with primary open-angle glaucoma and bilaterally instilled PGA eye drops to decrease intraocular pressure. His IPD had been recorded closely based on surgical microscope settings. The patient had a stable IPD for over five years before the use of PGA drops. The patient noticed IPD shortening associated with latanoprost usage since four years. The IPD shortened further twice with temporal switching to bimatoprost. However, the IPD partially recovered both the times on discontinuing the medication over the course of several months.

Conclusions and importance: Fluctuations in IPD with visible cosmetic changes occur in association with the use of topical PGA eye drops. There might be effects of PGA drops on binocular vision, which are possibly unaddressed and warrant further study.

Keywords: Deepening of upper eyelid; Glaucoma; Interpupillary distance; Prostaglandin; Prostaglandin-associated periorbitopathy.

Publication types

Case Reports