Microbotox: A prospective evaluation of dermatological improvement in patients with mild-to-moderate acne and erythematotelangiectatic rosacea

J Cosmet Dermatol. 2022 Sep;21(9):3747-3753. doi: 10.1111/jocd.14692. Epub 2022 Mar 21.

Abstract

Background: Botulin toxin (BTX) is a potent neurotoxin produced by the bacterium Clostridium botulinum, since its approval by FDA in 2002 for cosmetic purpose has been widely used. Recent studies indicate that it exerts its activity on various type of skin cells and can be used in some dermatological disease.

Objective: The aim of the study was to demonstrate how to use a peculiar dilution of botulinum toxin type A in the treatment of some dermatological disease like mild-to-moderate acne vulgaris and erythematotelangiectatic rosacea.

Material and methods: 50 patients were enrolled, 35 with mild-to-moderate acne and 15 with erythematotelangiectatic rosacea. Both group of patients were treated with a specific dilution of Onabotulinum toxin A called Microbotox. Patient images were taken before and 4 weeks after the treatment.

Results: The authors and patients were extremely satisfied with their treatments. There were no immediate or delayed complication in none of both group of patients.

Conclusion: Botulinum toxin shows a great promise either in dermatological disease like mild-to-moderate acne vulgaris and erythematotelangiectatic rosacea. Microbotox appears to be a valid, long-lasting, and a standardized approach to treat these kind of two disease.

Keywords: acne vulgaris; erythematotelangiectatic rosacea; microbotox; onabotulinumtoxin A.

MeSH terms

  • Acne Vulgaris* / complications
  • Acne Vulgaris* / drug therapy
  • Botulinum Toxins, Type A* / adverse effects
  • Cosmetic Techniques*
  • Humans
  • Neurotoxins
  • Rosacea* / drug therapy

Substances

  • Neurotoxins
  • Botulinum Toxins, Type A