Women of low income and education have lower levels of peripartum depression (PPD) literacy, limiting their ability to recognize symptoms and make informed healthcare decisions. Existing digital solutions and underlying development frameworks for PPD lack an integrative approach addressing health literacy and related disparities. Therefore, we develop an integrative framework for digital content engineering in PPD self-management consisting of (a) user needs analysis, (b) inclusion of eHealth literacy principles (science and health literacy), and (c) mapping user needs to the Behavioral Intervention Technology model. Results revealed that perinatal women seeking mental health care prefer information in multisensory formats, and knowledge needs were identified in areas such as medication management and coping with abnormal results. Results were mapped to eHealth literacy features of whiteboard videos covering essential PPD knowledge, and social media features where patients can articulate information needs. Initial evaluation of proposed features against existing PPD self-management solutions are discussed.
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