Epidemiology, reperfusion management, and outcomes of patients with myocardial infarction in Greece: The ILIAKTIS study

Hellenic J Cardiol. 2022 Sep-Oct:67:1-8. doi: 10.1016/j.hjc.2022.03.003. Epub 2022 Mar 17.

Abstract

Objective: Acute myocardial infarction (AMI) is one of the leading causes of death; however, updated data regarding clinical presentation and current management are missing in Greece. This study aimed to prospectively record the demographic and clinical characteristics of a representative sample of patients suffering from AMI, their management, and short-term outcomes.

Methods: ILIAKTIS is a national, prospective, multicenter, noninterventional study conducted under the auspices of Hellenic Society of Cardiology (HCS) and the European Initiative Stent - Save a Life. From 1st April 2020 to 30th June 2020, consecutive adult patients with STEMI or NSTEMI were enrolled in the 50 participating hospitals, appropriately selected to match the geographical and population distribution in the Greek territory.

Results: In total, 1862 patients (mean age: 64.2 ± 13.2 yrs.; 77.2% males) with AMI were enrolled. More patients presented with NSTEMI (56.8%) than with STEMI (43.2%). Primary PCI (pPCI) was the preferable treatment option for STEMI patients in PCI-hospitals (76.9% vs. 39.9% for non-PCI, p < .001) and thrombolysis in non-PCI-hospitals (47.3% vs. 17.9% for PCI-hospitals, p < .001). The mean length of hospital stay was 5.6 days. In-hospital mortality was less likely in NSTEMI compared to that in STEMI patients (aOR = 0.30; 95% CI 0.18 to 0.49). Patients initially admitted in non-PCI-hospitals showed increased risk for in-hospital (aOR = 2.29; 95% CI 1.20 to 4.42) and 30-day mortality (aOR = 1.88; 95% CI 1.20 to 2.96).

Conclusion: This study shows that the proportion of STEMI and NSTEMI patients managed interventionally has significantly increased, resulting in better clinical outcomes compared to previous Greek surveys.

Keywords: NSTEMI; STEMI; myocardial infarction; percutaneous coronary intervention; revascularization.

Publication types

  • Multicenter Study

MeSH terms

  • Adult
  • Aged
  • Female
  • Greece / epidemiology
  • Humans
  • Male
  • Middle Aged
  • Myocardial Infarction* / epidemiology
  • Myocardial Infarction* / therapy
  • Non-ST Elevated Myocardial Infarction* / epidemiology
  • Non-ST Elevated Myocardial Infarction* / etiology
  • Non-ST Elevated Myocardial Infarction* / therapy
  • Percutaneous Coronary Intervention* / adverse effects
  • Prospective Studies
  • Registries
  • Reperfusion
  • ST Elevation Myocardial Infarction* / epidemiology
  • ST Elevation Myocardial Infarction* / therapy
  • Time Factors