Identification of two novel B-cell epitopes on the nucleocapsid protein of porcine deltacoronavirus

Abstract

1. •

   Two monoclonal antibodies against newly emerged porcine deltacoronavirus nucleocapsid protein were prepared.

2. •

   The epitopes that these two monoclonal antibodies recognized on nucleocapsid protein were identified.

3. •

   The monoclonal antibody 6B7 recognized a linear epitope of N protein, while the 7F8 recognized a conformational epitope.

4. •

   Conservation of the identified epitopes between different coronaviruses was analyzed.