Management of peritoneal pseudomyxoma in pregnant women: A case report and review of the literature

J Gynecol Obstet Hum Reprod. 2022 May;51(5):102351. doi: 10.1016/j.jogoh.2022.102351. Epub 2022 Mar 15.

Abstract

The incidence of neoplasia during pregnancy is low, 1/1000 pregnancies. The most common cancers diagnosed during pregnancy are breast and cervical cancer. Pseudomyxoma peritonei (PMP) is a rare syndrome (1/1 000 000) characterized by the presence of gelatinous ascites and disseminated intra-peritoneal mucinous tumors. The origin of this syndrome is, in most of cases, a tumor of the appendix. A PMP diagnosis during pregnancy is an extremely rare event. We present the medical history of a 34-year-old woman diagnosed with a PMP at 29 weeks of amenorrhea, during the management of an ovarian masse. We preserved the pregnancy until 37 weeks of amenorrhea. She had a vaginal delivery. At 4 weeks post-partum, she had an extensive cytoreduction with intraperitoneal chemotherapy. We present literature review of PMP discover during pregnancy and a discussion about treatment of these PMP. We also discuss management of an ovarian masse diagnosis during pregnancy.

Keywords: Management in pregnancy; Ovarian mass; Pseudomyxoma peritonei.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Amenorrhea
  • Female
  • Humans
  • Ovarian Neoplasms* / diagnosis
  • Ovarian Neoplasms* / surgery
  • Peritoneal Neoplasms* / diagnosis
  • Peritoneal Neoplasms* / therapy
  • Pregnancy
  • Pregnant Women
  • Pseudomyxoma Peritonei* / diagnosis
  • Pseudomyxoma Peritonei* / surgery