Nephrotoxic Effects of Chemotherapeutic Agents

Clin J Oncol Nurs. 2022 Apr 1;26(2):219-223. doi: 10.1188/22.CJON.219-223.

Abstract

Nephrotoxicity can be a severe complication of oncology treatment. The most common presentations of chemotherapy-related renal disorders include acute kidney injury, electrolyte abnormalities, acid base disturbances, hemolytic anemia, and hypertension. Oncology nurses should be aware of the potential renal complications of oncology therapeutics and advocate for appropriate monitoring and treatment of patients. This article reviews the most common chemotherapeutic agents that may cause nephrotoxicity.

Keywords: acute kidney injury; chemotherapy; chronic kidney disease; nephrotoxicity.

Publication types

  • Review

MeSH terms

  • Acute Kidney Injury* / chemically induced
  • Antineoplastic Agents* / adverse effects
  • Drug-Related Side Effects and Adverse Reactions* / etiology
  • Humans
  • Kidney

Substances

  • Antineoplastic Agents