Solitary cutaneous infantile myofibroma as a hallmark of myofibromatosis: Two cases and review of the literature

Mitchell Braun; Micah Pascual; Thaddeus Mully; Andrew Phelps; Lori Prok; Sonal D Shah; Lucinda L Kohn

doi:10.1111/pde.14975

Solitary cutaneous infantile myofibroma as a hallmark of myofibromatosis: Two cases and review of the literature

Pediatr Dermatol. 2022 May;39(3):438-442. doi: 10.1111/pde.14975. Epub 2022 Mar 16.

Authors

Mitchell Braun¹, Micah Pascual², Thaddeus Mully³, Andrew Phelps⁴, Lori Prok⁵, Sonal D Shah^{3

6}, Lucinda L Kohn⁵

Affiliations

¹ University of California San Francisco School of Medicine, San Francisco, California, USA.
² University of Colorado Anschutz School of Medicine, Aurora, Colorado, USA.
³ Department of Dermatology, University of California, San Francisco, California, USA.
⁴ Department of Diagnostic Radiology, Oregon Health & Science University, Portland, Oregon, USA.
⁵ Department of Dermatology, University of Colorado Anschutz Medical College, Aurora, Colorado, USA.
⁶ Department of Dermatology, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.

PMID: 35297087
DOI: 10.1111/pde.14975

Abstract

Infantile myofibroma (IM) commonly presents as a benign cutaneous fibrous tumor in infancy. Although the majority of solitary IM regress without any morbidity, some cases have underlying bone or visceral involvement that can lead to both morbidity and mortality. In this report with review of the literature, we present two cases of solitary cutaneous IM with internal involvement and discuss screening cases of solitary IM with full body imaging.

Keywords: fibrous tumors; infantile myofibroma; pediatric dermatology.

Publication types

Case Reports
Review

MeSH terms

Bone and Bones
Humans
Myofibroma* / diagnosis
Myofibroma* / pathology
Myofibromatosis* / diagnosis
Myofibromatosis* / pathology
Skin Neoplasms* / diagnosis
Soft Tissue Neoplasms*