Objective: To review the application progress, mechanism, application points, limitations, and oncological safety of external volume expansion (EVE) assisted autologous fat grafting for breast reconstruction and provide a reference for optimizing the design of EVE.
Methods: Based on the latest relevant articles, the basic experiments and clinical applications of EVE were summarized.
Results: EVE can reduce interstitial fluid pressure, increase blood supply, and promote adipogenic differentiation, thereby benefiting the survival of transplanted fat. EVE assisted autologous fat grafting in clinical practice can improve the retention rate of breast volume and the outcome of breast reconstruction, meanwhile it doesn't increase the risk of local recurrence. But there is no standard parameters for application, and there are many complications and limitations.
Conclusion: EVE improves the survival of transplanted fat, but its complications and poor compliance are obvious, so it is urgent to further investigate customized products for breast reconstruction after breast cancer and establish relevant application guidelines.
目的: 总结体外扩张器（external volume expansion，EVE）辅助自体脂肪移植乳房再造的应用进展、作用机制、应用要点、局限性及肿瘤安全性，为优化EVE设计提供参考。.
方法: 结合近年相关文献，就EVE相关基础实验、临床应用做一综述。.
结果: EVE可降低组织间隙压、增加血供、促进脂肪细胞新生，从而有利于移植脂肪存活。临床应用EVE辅助自体脂肪移植可增加脂肪体积留存率，提升乳房重建效果，且不会增加乳腺癌患者局部复发率。但应用参数暂无标准，且应用并发症、局限性多。.
结论: EVE可促进移植脂肪存活，但存在并发症多、依从性差等缺点，亟需进一步研究开发乳腺癌术后乳房再造的专用产品并建立相关应用指南。.
Keywords: Breast reconstruction; breast cancer; external volume expansion; fat grafting.