Clinical characteristics of adults suffering from high-functioning autism and comorbid obsessive-compulsive disorder

Psychiatry Res. 2022 May:311:114498. doi: 10.1016/j.psychres.2022.114498. Epub 2022 Mar 9.

Abstract

Autism spectrum disorder (ASD) is a very heterogeneous disorder. Obsessive compulsive disorder (OCD) comorbidity, frequent in ASD, could be useful to define a specific ASD subtype. Our objective was to explore if adults with ASD and comorbid OCD could present a specific clinical profile of ASD in 89 high functioning-adult ASD patients. We found that adults with ASD and comorbid OCD showed a lower verbal IQ and a more severe impairments in social cognition. ASD with comorbid OCD present a specific clinical profile which could constitute a possible subtype of ASD.

Keywords: Autism spectrum disorder; Obsessive-compulsive disorder; Social cognition.

MeSH terms

  • Adult
  • Autism Spectrum Disorder* / complications
  • Autism Spectrum Disorder* / epidemiology
  • Autistic Disorder* / epidemiology
  • Comorbidity
  • Humans
  • Obsessive-Compulsive Disorder* / complications
  • Obsessive-Compulsive Disorder* / epidemiology
  • Social Cognition