Evaluation of Pulmonary Edema Using Ultrasound Imaging in Patients With COVID-19 Pneumonia Based on a Non-local Channel Attention ResNet

Ultrasound Med Biol. 2022 May;48(5):945-953. doi: 10.1016/j.ultrasmedbio.2022.01.023. Epub 2022 Feb 7.

Abstract

Recent research has revealed that COVID-19 pneumonia is often accompanied by pulmonary edema. Pulmonary edema is a manifestation of acute lung injury (ALI), and may progress to hypoxemia and potentially acute respiratory distress syndrome (ARDS), which have higher mortality. Precise classification of the degree of pulmonary edema in patients is of great significance in choosing a treatment plan and improving the chance of survival. Here we propose a deep learning neural network named Non-local Channel Attention ResNet to analyze the lung ultrasound images and automatically score the degree of pulmonary edema of patients with COVID-19 pneumonia. The proposed method was designed by combining the ResNet with the non-local module and the channel attention mechanism. The non-local module was used to extract the information on characteristics of A-lines and B-lines, on the basis of which the degree of pulmonary edema could be defined. The channel attention mechanism was used to assign weights to decisive channels. The data set contains 2220 lung ultrasound images provided by Huoshenshan Hospital, Wuhan, China, of which 2062 effective images with accurate scores assigned by two experienced clinicians were used in the experiment. The experimental results indicated that our method achieved high accuracy in classifying the degree of pulmonary edema in patients with COVID-19 pneumonia by comparison with previous deep learning methods, indicating its potential to monitor patients with COVID-19 pneumonia.

Keywords: COVID-19; Deep learning; Lung ultrasound; Pulmonary edema.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • COVID-19* / complications
  • COVID-19* / diagnostic imaging
  • Humans
  • Lung / diagnostic imaging
  • Pulmonary Edema* / complications
  • Pulmonary Edema* / diagnostic imaging
  • Respiratory Distress Syndrome* / complications
  • Respiratory Distress Syndrome* / diagnostic imaging
  • Ultrasonography