A method for intra-percardial PDT for malignant mesothelioma

Photodiagnosis Photodyn Ther. 2022 Jun:38:102799. doi: 10.1016/j.pdpdt.2022.102799. Epub 2022 Mar 9.

Abstract

We describe a case of a 35-year-old patient with recurrent non-resectable pleural mesothelioma cT4N0M0 with a confirmed malignant pericardial effusion, threatening for cardiac tamponade. We performed and described our experience of intrapericardial photodynamic therapy which was well tolerated and with a good survival result. After 12 months of follow-up our patient showed no signs of pericardial effusion and in stable condition, keeping high level of quality of life. This clinical case is an example of the excellent palliative effect of photodynamic therapy together with concomitant immunotherapy.

Keywords: Cancer-related pericardial effusion; Immunotherapy; Malignant pleural mesothelioma; Photodynamic therapy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Humans
  • Mesothelioma* / drug therapy
  • Mesothelioma, Malignant*
  • Pericardial Effusion* / complications
  • Pericardial Effusion* / drug therapy
  • Photochemotherapy* / methods
  • Pleural Neoplasms* / drug therapy
  • Quality of Life