Disseminated Aspergillus lentulus Infection in a Heart Transplant Recipient: A Case Report

Clin Infect Dis. 2022 Sep 30;75(7):1235-1238. doi: 10.1093/cid/ciac205.

Abstract

We present the first published case of successfully treated disseminated Aspergillus lentulus infection in a solid organ transplant recipient with invasive pulmonary disease, endophthalmitis, and a cerebral abscess. This case highlights important challenges associated with treating A. lentulus, particularly regarding antifungal resistance and toxicities associated with long-term antifungal therapy.

Keywords: Aspergillus lentulus; case report; endophthalmitis; invasive aspergillosis; solid organ transplant.

Publication types

  • Case Reports

MeSH terms

  • Antifungal Agents* / pharmacology
  • Antifungal Agents* / therapeutic use
  • Aspergillus
  • Drug Resistance, Fungal
  • Heart Transplantation* / adverse effects
  • Humans

Substances

  • Antifungal Agents

Supplementary concepts

  • Aspergillus lentulus