Melatonin increased hypoxia-inducible factor (HIF) by inhibiting prolyl hydroxylase: A hypothesis for treating anaemia, ischaemia, and covid-19

Clin Exp Pharmacol Physiol. 2022 Jun;49(6):696-698. doi: 10.1111/1440-1681.13639. Epub 2022 Mar 25.

Authors

Mohammad Hossein Hosseinzadeh¹, Amin Goodarzi², Mohammad Malekan³, Mohammad Ali Ebrahimzadeh¹

Affiliations

¹ Pharmaceutical Sciences Research Center, School of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.
² Department of Medicinal Chemistry, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.
³ Student Research Committee, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

No abstract available

Publication types

Letter

MeSH terms

Anemia* / drug therapy
COVID-19*
Humans
Hypoxia
Hypoxia-Inducible Factor 1, alpha Subunit
Ischemia
Melatonin* / pharmacology
Melatonin* / therapeutic use
Prolyl Hydroxylases

Substances

Hypoxia-Inducible Factor 1, alpha Subunit
Prolyl Hydroxylases
Melatonin