Harnessing the Natural Toxic Metabolites in COVID-19

Ali Bahrami; Mohammad Taheri; Mohammad Reza Arabestani; Meysam Soleimani; Mojdeh Mohammadi; Fatemeh Golabchi; Maryam Banitorfi; Seyed Mostafa Hosseini; Sodabe Khodabandehlou; Fatemeh Nouri

doi:10.1155/2022/3954944

Harnessing the Natural Toxic Metabolites in COVID-19

Evid Based Complement Alternat Med. 2022 Mar 7:2022:3954944. doi: 10.1155/2022/3954944. eCollection 2022.

Authors

Affiliations

¹ Student Research Committee, Hamadan University of Medical Sciences, Hamadan, Iran.
² Department of Pharmaceutical Biotechnology, School of Pharmacy, Hamadan University of Medical Scienceaffs, Hamadan, Iran.
³ Department of Microbiology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
⁴ Department of Pharmacology and Toxicology, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran.

Abstract

SARS-CoV-2 is a novel coronavirus and the cause of the recent pandemic; it is an enveloped β-coronavirus. SARS-CoV-2 appear in the Wuhan City of China for the first time and outspread worldwide quickly. Due to its person-to-person fast transmission, COVID-19 is becoming a global problem. SARS-CoV-2 enter into cells by using ACE2 receptors that are numerous in the lungs and finally can cause acute respiratory distress syndrome (ARDS). Dry cough, sore throat, fever, body pain, headache, GIT discomfort, diarrhoea, and fatigue are some of the COVID-19 symptoms. There is no definite and certain treatment for disease caused by SARS-CoV-2 till now. Some pharmacological effects of toxins, toxoids, and venoms have been proven, and their effects on some diseases have been evaluated. This study aimed to investigate the role of toxins, toxoids, and venom in the pathophysiology of COVID-19 disease.

Publication types

Review