SLiMs go viral! One more weapon against interferon

Lisa Miorin; Maria Teresa Sanchez-Aparicio

doi:10.1016/j.chom.2022.02.012

SLiMs go viral! One more weapon against interferon

Cell Host Microbe. 2022 Mar 9;30(3):286-288. doi: 10.1016/j.chom.2022.02.012.

Authors

Lisa Miorin¹, Maria Teresa Sanchez-Aparicio²

Affiliations

¹ Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: lisa.miorin@mssm.edu.
² Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: maria.t.sanchez@mssm.edu.

PMID: 35271801
DOI: 10.1016/j.chom.2022.02.012

Abstract

In this issue of Cell Host & Microbe, Talbot-Cooper et al. highlight how viruses develop strategies that can target universal activators of the innate immune response. The authors unravel a common mechanism between poxviruses and paramyxoviruses to limit the expression of antiviral genes and promote virulence.

Publication types

Comment

MeSH terms

Antiviral Agents
Immunity, Innate
Interferons*
Virulence
Viruses* / genetics
Viruses* / immunology

Substances

Antiviral Agents
Interferons