Fungi make fun guys

Cell Host Microbe. 2022 Mar 9;30(3):277-278. doi: 10.1016/j.chom.2022.02.009.

Abstract

In a recent Cell study, Leonardi et al. show that commensal mucosa-associated gut fungi profoundly impact host immunity, epithelial barrier function, and, unexpectedly, neuroimmune modulation of social behavior. All of these events are controlled by fungal-induced activation of type 17 cytokines that act on both epithelial cells and neurons.

Publication types

  • Comment

MeSH terms

  • Cytokines / metabolism
  • Epithelial Cells / immunology
  • Fungi* / immunology
  • Symbiosis*

Substances

  • Cytokines