Endoscopic Management of GERD

Dig Dis Sci. 2022 May;67(5):1455-1468. doi: 10.1007/s10620-022-07390-2. Epub 2022 Mar 8.

Abstract

Gastroesophageal reflux disease (GERD) has consistently been the most frequently diagnosed gastrointestinal malady in the USA. The mainstay of therapy has traditionally been medical management, including lifestyle and dietary modifications as well as antacid medications. In those patients found to be refractory to medical management or with a contraindication to medications, the next step up has been surgical anti-reflux procedures. Recently, though innovative advancements in therapeutic endoscopy have created numerous options for the endoscopic management of GERD, in this review, we discuss the various endoscopic therapy options, as well as suggested strategies we use to recommend the most appropriate therapy for patients.

Keywords: Endoscopic suturing; Esophyx; Gastroesophageal reflux disease; Overstitch; Resection and plication; Stretta; Transoral incisionless fundoplication.

Publication types

  • Review

MeSH terms

  • Anti-Ulcer Agents* / therapeutic use
  • Endoscopy
  • Esophagitis, Peptic* / drug therapy
  • Fundoplication / methods
  • Gastroesophageal Reflux* / drug therapy
  • Gastroesophageal Reflux* / surgery
  • Humans
  • Treatment Outcome

Substances

  • Anti-Ulcer Agents