Times to endovascular treatment following two triage models

Neurol Sci. 2022 Jun;43(6):3967-3971. doi: 10.1007/s10072-022-05995-z. Epub 2022 Mar 7.

Abstract

Introduction: Debate is ongoing regarding the best service model for achieving a prompt recanalization in LVO ischemic stroke with an indication for thrombectomy. We aim to assess differences between two of the existing models within our region.

Methods: We work in a cluster of three public hospitals (one hub and two spokes) forming a single functional neurology service in Madrid (Spain). Upon a LVO case out of regular hours, the interventional neuroradiologist drives to the hub hospital following the drive-the-doctor paradigm (DD). For any of the spokes, the patient is transferred to the nearest endovascular-capable hospital (drip-and-ship-DS) following the Madrid Stroke Plan. We compared times to endovascular procedures between cases managed under each model.

Results: Thirty-eight patients in the period April 2014-March 2021 meet the inclusion criteria (DD 27; DS 11). While baseline characteristics are comparable between groups, we observed a notable difference in the time delays favoring those managed under the DD model; with differences between median times of 105 min for hospital arrival-groin puncture (DD 140 [110-181]; DS 245 [222-310], p 0.0004); 122 min for CT-groin puncture (DD 100 [85-144]; DS 222 [200-255], p = 0.0001); and 98 min for hospital arrival-recanalization (DD 180 [140-209]; DS 278 [241-360], p = 0.0014). No differences were observed for NIHSS or mRS on discharge.

Conclusions: Compared to the drip-and-ship, the drive-the-doctor triage model for patients with LVO ischemic stroke in primary centers seems to guarantee a shorter time to the start of the endovascular procedure and to recanalization in our region.

Keywords: Emergency Care; Ischemic Stroke; Prognosis; Stroke; Thrombectomy.

MeSH terms

  • Brain Ischemia* / diagnostic imaging
  • Brain Ischemia* / surgery
  • Endovascular Procedures* / methods
  • Humans
  • Ischemic Stroke*
  • Patient Transfer
  • Retrospective Studies
  • Stroke* / diagnostic imaging
  • Stroke* / surgery
  • Thrombectomy / methods
  • Thrombolytic Therapy / methods
  • Time-to-Treatment
  • Treatment Outcome
  • Triage