Validation of a European Spanish adaptation of the Apathy Evaluation Scale-self-rated version (AES-S) in patients with schizophrenia

Clara Martínez-Cao; Leticia García-Álvarez; Teresa Bobes-Bascarán; Lorena de la Fuente-Tomás; Emilio Fernández-Egea; Ángela Velasco; Leticia González-Blanco; Paula Zurrón-Madera; Eduardo Fonseca-Pedrero; Pilar A Sáiz-Martínez; María Paz García-Portilla; Julio Bobes

doi:10.1016/j.rpsmen.2020.04.007

Validation of a European Spanish adaptation of the Apathy Evaluation Scale-self-rated version (AES-S) in patients with schizophrenia

Rev Psiquiatr Salud Ment (Engl Ed). 2022 Jan-Mar;15(1):22-28. doi: 10.1016/j.rpsmen.2020.04.007.

Affiliations

¹ Dpto. Psiquiatría, ISPA, Universidad de Oviedo, Oviedo, Spain.
² Dpto. Psiquiatría, CIBERSAM, ISPA, Universidad de Oviedo, Oviedo, Spain.
³ Dpto. Psiquiatría, University of Cambridge, Cambridge, United Kingdom.
⁴ Dpto. Psiquiatría, CIBERSAM, Universidad de Oviedo, Oviedo, Spain.
⁵ Dpto. Psiquiatría, SESPA, Universidad de Oviedo, Oviedo, Spain.
⁶ Dpto. Psiquiatría, Universidad de la Rioja, CIBERSAM, La Rioja, España.
⁷ Dpto. Psiquiatría, CIBERSAM, Universidad de Oviedo, Oviedo, Spain. Electronic address: pazportilla@gmail.com.

PMID: 35256069
DOI: 10.1016/j.rpsmen.2020.04.007

Abstract

Introduction: Apathy is a negative symptom of schizophrenia and is associated with poor real world functioning. Therefore, it is important to have validated psychometric instruments to assess this symptom. This is the first study to validate the Spanish adaptation of the self-rated version of the Apathy Assessment Scale (AES-S) in patients with schizophrenia.

Materials and methods: Naturalistic, cross-sectional, validation study in 104 patients with schizophrenia evaluated using the following scales: Clinical Global Impression-Severity (CGI-S), Personal and Social Performance (PSP), Clinical Assessment Interview for Negative Symptoms (CAINS), Self-report of Negative Symptoms (SNS), Motivation and Pleasure Scale-Self-Report (MAP-SR), Calgary Depression Scale for Schizophrenia (CDSS), and Apathy Evaluation Scale-self-rated version (AES-S).

Results: Reliability: Internal consistency (Cronbach's alpha) was 0.908. Convergent validity: The Pearson correlation coefficient between AES-S and CAINS-MAP total scores was -0.483 (p<0.001). For SNS, total and avolition subscale scores were -0.803 and -0.639 (p<0.001), respectively. With the MAP-SR, the correlation coefficient was -0.727 (p<0.001). Divergent validity: The Pearson correlation coefficient between AES-S and PSP total scores was 0.504 (p<0.001). Furthermore, with the CDSS, the correlation coefficient was -0.431 (p<0.001). Discriminant validity: The AES-S discriminated between different levels of illness severity according to CGI-S scores. Factor analysis: A three-component solution explained 57.32% of the variance. Pearson correlations between coefficients were 1-2=0.265, 1-3=0.464, and 2-3=0.060.

Conclusion: The Spanish AES-S is a reliable and valid instrument for assessing apathy in Spanish patients with schizophrenia. It seems to be appropriate for use in everyday clinical practice as a means of monitoring apathy in these patients.

Keywords: AES-S; Apathy; Apatía; Esquizofrenia; Propiedades psicométricas; Psychometric properties; Schizophrenia.

MeSH terms

Apathy*
Cross-Sectional Studies
Humans
Psychiatric Status Rating Scales
Reproducibility of Results
Schizophrenia* / diagnosis