Disasters cause death, trauma, and psychological distress. Comprising the largest number of healthcare workers, nurses play a crucial role in reducing the impact of a disaster. The objective of this review is to identify the factors that influence nurses' ability during a disaster emergency response to provide adequate care. This research was conducted by doing a literature search from the Pro-Quest and Science-Direct databases using the PRISMA-ScR to screen the articles. The final results included 13 articles. An analysis was performed to identify themes in line with the purpose of the review. All factors affecting nurses' ability to respond to a disaster situation were classified into three themes: 1) factors increasing nurses' ability, 2) barriers to delivering effective nursing care, and 3) support needed to maintain the nurses' ability. During an emergency situation due to a disaster, adequate knowledge and skill to save lives, treat injuries, manage stress and coordinate between teams are the basic competencies needed for optimal care. Nurses' clinical experience or previous disaster experience and training could increase nurses' adaptability in disaster conditions. Support from nurses' workplace and proper implementation of disaster management policy enhance nurses' services and prevent barrier under disaster condition. The results emphasize that future training should aim for improving nurses' knowledge and skills, including the knowledge of nurses' family to protect themselves and deal with disasters. Such knowledge increased family preparedness, which is an important factor to enhance nurses' willingness to work following a disaster.