The emerging roles of ATG1/ATG13 kinase complex in plants

Qiuling Wang; Suiwen Hou

doi:10.1016/j.jplph.2022.153653

The emerging roles of ATG1/ATG13 kinase complex in plants

J Plant Physiol. 2022 Apr:271:153653. doi: 10.1016/j.jplph.2022.153653. Epub 2022 Mar 2.

Authors

Qiuling Wang¹, Suiwen Hou²

Affiliations

¹ Key Laboratory of Cell Activities and Stress Adaptations, Ministry of Education, School of Life Sciences, Lanzhou University, Lanzhou, 730000, People's Republic of China.
² Key Laboratory of Cell Activities and Stress Adaptations, Ministry of Education, School of Life Sciences, Lanzhou University, Lanzhou, 730000, People's Republic of China. Electronic address: housw@lzu.edu.cn.

PMID: 35255243
DOI: 10.1016/j.jplph.2022.153653

Abstract

Autophagy is a conserved system from yeast to mammals that mediates the degradation and renovation of cellular components. This process is mainly driven by numerous autophagy-related (ATG) proteins. Among these components, the ATG1/ATG13 complex plays an essential role in initiating autophagy, sensing nutritional status signals, recruiting downstream ATG proteins to the autophagosome formation site, and governing autophagosome formation. In this review, we will focus on the ATG1/ATG13 kinase complex, summarizing and discussing the current views on the composition, structure, function, and regulation of this complex in plants.

Keywords: ATG1; ATG11; ATG13; Autophagy; Plants; Regulation.

Publication types

Review

MeSH terms

Animals
Autophagy* / physiology
Autophagy-Related Proteins
Plants / enzymology
Protein Serine-Threonine Kinases*
Transcription Factors

Substances

Autophagy-Related Proteins
Transcription Factors
Protein Serine-Threonine Kinases