Severe Anemia Caused by Gastric Antral Vascular Ectasia and Autoimmune Gastritis

Intern Med. 2022 Oct 1;61(19):2873-2876. doi: 10.2169/internalmedicine.9225-21. Epub 2022 Mar 5.

Abstract

An 80-year-old man presented to our hospital with general fatigue on exertion that had gradually worsened over 6 months. His blood test revealed severe anemia, and gastroscopy revealed findings consistent with gastric antral vascular ectasia (GAVE) and autoimmune gastritis. We diagnosed the patient with severe anemia caused by GAVE and autoimmune gastritis. The present case suggested that GAVE is triggered by autoimmune gastritis, and the mechanism is likely related to hypergastrinemia. The reporting of this rare case may help elucidate the cause of GAVE, which is currently unknown.

Keywords: autoimmune gastritis; gastric antral vascular ectasia; hypergastrinemia; iron deficiency; severe anemia; vitamin B12 deficiency.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Anemia* / etiology
  • Gastric Antral Vascular Ectasia* / complications
  • Gastric Antral Vascular Ectasia* / diagnosis
  • Gastritis* / complications
  • Gastritis* / diagnosis
  • Gastroscopy / adverse effects
  • Humans
  • Male