Commentary for an article on spin trapping of superoxide and hydroxyl radical: Practical aspect

Toshihiko Ozawa; Ikuo Nakanishi

doi:10.1016/j.abb.2022.109153

Commentary for an article on spin trapping of superoxide and hydroxyl radical: Practical aspect

Arch Biochem Biophys. 2022 Mar 2:720:109153. doi: 10.1016/j.abb.2022.109153. Online ahead of print.

Authors

Toshihiko Ozawa¹, Ikuo Nakanishi²

Affiliations

¹ Nihon Pharmaceutical University, 10281 Komuro, Ina-machi, Kitaadachi-Gun, Saitama, 362-0806, Japan. Electronic address: ozawa@rugbygoods.com.
² Quantum RedOx Chemistry Group, Institute for Quantum Life Science, Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, 9-4-1, Anagawa, Inage-ku, Chiba, 263-8555, Japan.

PMID: 35247362
DOI: 10.1016/j.abb.2022.109153

Abstract

This commentary describes a highly cited paper by Eli Finkelstein, Gerald M. Rosen, and Elmer J. Raukman that appeared in Archives of Biochemistry and Biophysics published in 1980. They reviewed many reports being regularly appearing in the literature describing spin trapping and hydroxyl radicals from various sources and contributed to the development and progress that has been made in oxidative stress research.

Keywords: Electron paramagnetic resonance (EPR); Hydroxyl radical; Superoxide; pin trapping.

Publication types

Review