Uncommon presentation of brown tumours revealing hyperparathyroidism: Three case reports

Mod Rheumatol Case Rep. 2023 Jan 3;7(1):219-222. doi: 10.1093/mrcr/rxac015.

Abstract

Brown tumours (BTs) are focal bone lesions encountered in patients with uncontrolled hyperparathyroidism (HPT). They are due to a proliferation of multinucleated giant cells in osteolytic lesions. Because of early screening of bone metabolism disorders, BTs are rare bone manifestations. More importantly, they scarcely reveal the disease. We demonstrate through these two cases reports unusual locations of BT complicating the course of HPT due to parathyroid hyperplasia.

Keywords: Hyperparathyroidism; brown tumours; parathyroid adenoma.

Publication types

  • Case Reports

MeSH terms

  • Diagnosis, Differential
  • Humans
  • Hyperparathyroidism, Primary* / complications
  • Hyperparathyroidism, Primary* / diagnosis
  • Neoplasms* / complications
  • Neoplasms* / diagnosis
  • Osteitis Fibrosa Cystica* / complications
  • Osteitis Fibrosa Cystica* / etiology
  • Osteolysis*