Comparison of ASSR, ABR and 40 Hz AERP Response Thresholds at Different Frequencies and Their Forensic Applications

Xin-Yuan Zhang; Fang-Liang Luo; Long-Long Cheng; Yan-He Xiong; Ji-Hui Liu

doi:10.12116/j.issn.1004-5619.2020.200913

Comparison of ASSR, ABR and 40 Hz AERP Response Thresholds at Different Frequencies and Their Forensic Applications

Fa Yi Xue Za Zhi. 2021 Dec 25;37(6):813-816. doi: 10.12116/j.issn.1004-5619.2020.200913.

[Article in English, Chinese]

Authors

Xin-Yuan Zhang¹, Fang-Liang Luo^{1

2}, Long-Long Cheng^{1

3}, Yan-He Xiong^{1

4}, Ji-Hui Liu^{1

2}

Affiliations

¹ Department of Forensic Clinical Medicine, School of Forensic Medicine, China Medical University, Shenyang 110122, China.
² Liaoning University Expert Evidence Center, Academy of Forensic Science Liaoning University, Shenyang 110036, China.
³ Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, Liaoning Province, China.
⁴ Shanghai Love Nursing Station, Shanghai 200030, China.

PMID: 35243846
DOI: 10.12116/j.issn.1004-5619.2020.200913

Abstract
in English, Chinese

Objectives: To explore the relationship between the frequency characteristics and response threshold of auditory steady-state response (ASSR), auditory brainstem response (ABR) and 40 Hz auditory event related potential (40 Hz AERP), and their application values in forensic medicine.

Methods: Thirty volunteers with normal hearing (60 ears) were selected to perform pure tone audiometry (PTA) threshold and ASSR, ABR and 40 Hz AERP response threshold tests in the standard sound insulation shielding room, and the results were statistically analyzed by SPSS 22.0 software.

Results: At 0.5 kHz and 1.0 kHz frequencies, the correlation between 40 Hz AERP response threshold and PTA threshold was good, which was better than that of ASSR and ABR response threshold. At 2.0 kHz and 4.0 kHz frequencies, the correlation between ASSR and ABR response thresholds and PTA threshold was good, which was better than that of 40 Hz AERP response threshold.

Conclusions: To evaluate the hearing at 0.5 kHz and 1.0 kHz frequencies, it is recommended to use 40 Hz AERP and ASSR to comprehensively assess the PTA threshold of the subjects. To evaluate the hearing at 2.0 kHz and 4.0 kHz frequencies, ABR and ASSR are recommended to assess the PTA threshold of subjects comprehensively. The combination of ASSR, ABR and 40 Hz AERP can improve the accuracy of hearing function evaluation.

目的: 探讨听性稳态反应（auditory steady-state response，ASSR）与听性脑干反应（auditory brainstem response，ABR）、40 Hz听觉相关电位（40 Hz auditory event related potential，40 Hz AERP）的频率特性和反应阈值之间的关系及法医学应用价值。方法: 选择听力正常的志愿者30名（60耳），在标准隔声屏蔽室内，进行纯音测听（pure tone audiometry，PTA）阈值和ASSR、ABR、40 Hz AERP反应阈值测试，并采用SPSS 22.0软件对结果进行统计分析。结果: 0.5 kHz和1.0 kHz频率，40 Hz AERP反应阈值与PTA阈值具有较好的相关性，并且优于ASSR和ABR反应阈值。2.0 kHz和4.0 kHz频率，ASSR和ABR反应阈值与PTA阈值具有较好的相关性，并且优于40 Hz AERP反应阈值。结论: 判断0.5 kHz和1.0 kHz频率的听力，建议采用40 Hz AERP和ASSR综合判断受试者的PTA阈值；判断2.0 kHz和4.0 kHz频率的听力，建议采用ABR和ASSR综合判断受试者的PTA阈值。通过ASSR、ABR、40 Hz AERP的组合可提高听觉功能评价的准确性。.

Keywords: 40 Hz auditory event related potential (40 Hz AERP); auditory brainstem response (ABR); auditory steady-state response(ASSR); forensic medicine; pure tone audiometry (PTA); threshold.

MeSH terms

Acoustic Stimulation / methods
Audiometry, Evoked Response
Audiometry, Pure-Tone
Auditory Threshold / physiology
Evoked Potentials, Auditory, Brain Stem* / physiology
Forensic Medicine
Hearing* / physiology
Humans

Abstract in English, Chinese

MeSH terms

Abstract
in English, Chinese