Antibacterial properties of poly (N, N-dimethylaminoethyl methacrylate) obtained at different initiator concentrations in solution polymerization

Dawid Stawski; Karolina Rolińska; Dorota Zielińska; Priyanka Sahariah; Martha Á Hjálmarsdóttir; Már Másson

doi:10.1098/rsos.211367

Antibacterial properties of poly (N, N-dimethylaminoethyl methacrylate) obtained at different initiator concentrations in solution polymerization

R Soc Open Sci. 2022 Jan 12;9(1):211367. doi: 10.1098/rsos.211367. eCollection 2022 Jan.

Authors

Dawid Stawski¹, Karolina Rolińska¹, Dorota Zielińska^{1

2}, Priyanka Sahariah³, Martha Á Hjálmarsdóttir⁴, Már Másson³

Affiliations

¹ Institute of Material Technologies of Textiles and Polymer Composites, Lodz University of Technology, Lodz, Poland.
² R&D Project Department, Institute of Security Technologies 'MORATEX', Lodz, Poland.
³ Faculty of Pharmaceutical Sciences, School of Health Sciences, University of Iceland, Reykjavík, Iceland.
⁴ Faculty of Medicine, Department of Biomedical Science, University of Iceland, Stapi, Hringbraut 31,101 Reykjavík, Iceland.

Abstract

The samples of poly(N,N-dimethylaminoethyl methacrylate) were synthesized by radical polymerization. The amount of monomer and solvent was constant as opposed to an amount of initiator which was changing. No clear relationship between polymerization conditions and the molecular weight of the polymer was found, probably due to the branched configuration of produced polymer. Bactericidal interactions in all samples against Gram-positive and Gram-negative bacteria have been demonstrated. However, the observed effect has various intensities, depending on the type of bacteria and the type of sample.

Keywords: antimicrobial properties; poly(N,N-dimethylaminoethyl methacrylate); polymerization.

Associated data

figshare/10.6084/m9.figshare.c.5764223