Medicine before and after David Cox

Pavlos Msaouel; Paula Jimenez-Fonseca; Bora Lim; Alberto Carmona-Bayonas; Giancarlo Agnelli

doi:10.1016/j.ejim.2022.02.022

Medicine before and after David Cox

Eur J Intern Med. 2022 Apr:98:1-3. doi: 10.1016/j.ejim.2022.02.022. Epub 2022 Feb 28.

Authors

Pavlos Msaouel¹, Paula Jimenez-Fonseca², Bora Lim³, Alberto Carmona-Bayonas⁴, Giancarlo Agnelli⁵

Affiliations

¹ Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, United States of America. Electronic address: PMsaouel@mdanderson.org.
² Medical Oncology Department. Hospital Universitario Central de Asturias. Avenida de Roma s/n, Oviedo Asturias. Spain.
³ Breast Oncology, Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX, United States of America. Electronic address: Bora.Lim@bcm.edu.
⁴ Hematology and Medical Oncology Department, Hospital Universitario Morales Meseguer. UMU. IMIB. Murcia. Spain.
⁵ Internal Vascular and Emergency Medicine-Stroke Unit, University of Perugia, Perugia, Italy.

PMID: 35241350
DOI: 10.1016/j.ejim.2022.02.022

Abstract

Herein we recount the legacy of Sir David Roxbee Cox (15 July 1924 - 18 January 2022) from the perspective of practicing clinicians. His-pioneering work in developing the logistic and Cox proportional hazard regression models revolutionized the analysis and interpretation of categorical and time-to-event survival outcomes in modern medicine. This legacy is an inspiration for all those who follow on Sir David Cox's path.

Keywords: Binary logistic regression; David Cox; David cox; History; Proportional hazards model; survival analysis.

Publication types

Editorial

MeSH terms

Humans
Proportional Hazards Models
Survival Analysis*